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CEMEF trainee position : Fluorescence amplification in bio-aerogel

Postée le 23 mar.

Lieu : Centre de mise en forme des Matériaux (CEMEF), à Sophia-Antipolis, Valbonne, France · Contrat : Stage · Rémunération : Gratification: about 550 €/month. €

Société : MINES ParisTech – CEMEF

CEMEF, which stands for Centre de Mise en Forme des Matériaux, or Centre for Material Forming, is a leading research centre in the field of material forming. It was created in 1974 and is located in the Sophia Antipolis science park, near Nice in the south of France. It is a research laboratory of MINES ParisTech and has been associated with CNRS, the French National Science Foundation since 1979.
CEMEF develops global approaches in material forming (polymers, bio-polymers, elastomers, metals, alloys...), combining physics, physical chemistry, mechanics, thermics, modelling, numerical simulation (finite element methods, meshing, fluid-structure coupling...). The scientific developments are applied to forming processes: injection molding, extrusion, forging, machining, rolling, welding... It has about 160 people, including 70 PhD students.

Description du poste

Project description
Fluorescence is widely used in biology and medicine for the detection, quantification and imaging of various structures. However, detect rare “markers” remains a challenge, and various amplification options are under research. One of the directions is using the physical principle of random lasers and the multiple scattering of light. As fluorescence detection is targeted to bio-medical applications, non-toxic components should be used. So-called biological lasers that use biological conditions is now a hot topic.
In this work we want to use new fully bio-based materials, bio-aerogels, to act as fluorescence amplifiers. Bio-aerogels are ultra-light, highly porous and nanostructured materials based on natural polymers that are biocompatible. Bio-aerogels possess a strong potential for a variety of applications in life sciences and in biomass valorisation.
The goal of this work is to prepare bio-aerogels and test them as fluorescence amplifiers.
In this internship, the student will prepare aerogels from cellulose solutions incorporating particles with very high refractive index. Density, morphology and specific surface area of aerogels will be characterised. Fluorescence intensity will then be measured and correlated with aerogel properties.
The work is at the at the frontier of materials’ science and physics (interactions light/matter, scattering). It will involve the use of various techniques, including formulation, rheology, optical and electron microscopies, aerogel characterisation and fluorescence spectroscopy.
Most of the work will be performed in CEMEF in close collaboration with two neighbouring Institutes, IPMC and INPHYNI. CEMEF is world leader in the development of biomass-based materials, in particular, of bio-aerogels. INPHYNI is well-known for its work in optical physics and the IPMC is specialized among others, in neuroscience, ion channels at the central or peripheral level; the understanding the role of the non-coding genome, the curvature of cell membranes, etc.

Duration : 6 months

Profil recherché

Skills: knowledge in polymer physics and in optics, capability to work in group, motivation and sense of initiative and capability to report regularly on his/her work.

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Application:
The position is for an undergraduate student, at the level of the final Master degree project. Expertise in physics, chemical physics of materials, and/or materials engineering is expected.
Please send your CV, motivation letter, your marks from the last two years and email of a reference person to Tatiana Budtova, CEMEF, tel : +33 (0)4 93 95 74 70; email : tatiana.budtova@mines-paristech.fr